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In the absence of vitamin B12 supplementation, unusually high vitamin B12 levels in the bloodstream may sometimes indicate underlying health conditions, including: 10 Several forms of liver disease, such as acute hepatitis, cirrhosis, and liver cancer Certain blood cancers, including leukemia and polycythemia vera Hypereosinophilic syndrome, a group of blood disorders that may lead to organ damage 11 Does Having High Vitamin B12 Levels Mean Cancer

View at Publisher | View at Google Scholar Enebo LB, Berthelsen KK, Kankam M, Lund MT, Rubino DM, et al

Plus, LL-37 could be protumorigenicmeaning it could cause tumors to developin some tissues

Practical Interpretation The mechanistic plausibility (NNMT NAD SIRT1/PGC-1 BMR & fat oxidation) is strong and consistent across preclinical models